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The most direct evidence in support of the first conclusion is that training caused a ificant decrease in escape latency and ificant increase in both the percentage of swim time and path length spent in the target quadrant by training d 7 relative Sext text ladies xxx buddy thickfat girls performance on d 2 of training. Collectively, these data are interpreted as spatial learning because the mice require less time to find the platform and spend more time and path length in the target quadrant, Large lady seeks man they have learned the platform location relative to Gl mwm looking for an experienced female fister extra-maze visual cues [ 42 ]. The observed escape latencies are comparable to those recently reported in a study that demonstrated a reduction in MWM escape latency over a 5 d training period in PND 35 male offspring of exercised male mice [ 43 ]. Interestingly, the same study showed a much more modest decrease in escape latency of male offspring of unexercised male mice, indicating that performance of the weanling mouse in the MWM can be variable, and that the training paradigm presented here induces more robust spatial learning.

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Female crebalphadelta- deficient mice show earlier age-related cognitive deficits than males. the publisher's final edited version of this article is available at neuroscience see other articles in pmc that cite the published article.

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